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Identifying specific Notch1 target proteins in lung carcinoma cells.
Histology and Histopathology ( IF 2 ) Pub Date : 2020-10-23 , DOI: 10.14670/hh-18-271
Wael Abdo Hassan 1, 2 , Takaaki Ito 3
Affiliation  

The Notch signaling pathway has different roles in many human neoplasms, being either tumor-promoting or anti-proliferative. In addition, Notch signaling in carcinogenesis can be tissue dependent. The aim of the current study is to elucidate the relation between Notch1 protein expression in lung cancer cells and the following Notch related proteins: Hes1, c-Myc, Jagged1 and Jagged2.

中文翻译:

鉴定肺癌细胞中的特定 Notch1 靶蛋白。

Notch 信号通路在许多人类肿瘤中具有不同的作用,可以促进肿瘤或抗增殖。此外,致癌作用中的 Notch 信号传导可能是组织依赖性的。本研究的目的是阐明肺癌细胞中 Notch1 蛋白表达与以下 Notch 相关蛋白之间的关系:Hes1、c-Myc、Jagged1 和 Jagged2。
更新日期:2020-10-27
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