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Novel imaging techniques using 18F‐florbetapir PET/MRI can guide fascicular nerve biopsy in amyloid multiple mononeuropathy
Muscle & Nerve ( IF 3.4 ) Pub Date : 2020-10-23 , DOI: 10.1002/mus.27100
Kamal Shouman 1 , Stephen M. Broski 2 , Eli Muchtar 3 , Courtney A. Pendleton 4 , Geoffrey B. Johnson 2 , Jennifer Tracy 1 , Janean K. Engelstad 5 , Robert J. Spinner 4 , P. James B. Dyck 1
Affiliation  

Multiple mononeuropathy is a rare presentation of primary (AL) amyloidosis and nerve biopsy is usually needed for diagnosis. Conventional imaging is useful to identify proximal nerve involvement but may be inadequate. We report a patient with multiple mononeuropathy whose presentation was suggestive of AL amyloid neuropathy and in whom repeated tissue biopsies were negative for amyloid (including two sensory nerves and one muscle).

中文翻译:

使用18F-florbetapir PET / MRI的新颖成像技术可指导淀粉样多发性单神经病的束状神经活检

多发性单神经病是原发性(AL)淀粉样变性的罕见表现,诊断通常需要神经活检。常规成像可用于识别近端神经受累,但可能不足。我们报告了一名多发性单神经病患者,其表现提示AL淀粉样蛋白神经病,并且其反复组织活检显示淀粉样蛋白阴性(包括两条感觉神经和一条肌肉)。
更新日期:2020-12-21
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