Nanomedicine: We present a novel nanomedicine consisting of a RAPTA metal‐based drug immobilised onto the surface of polyacrylamide nanoparticles. Our conjugates have been well characterised, and their effects on cell viability evaluated through in vitro MTT cytotoxicity assays against HT‐29 colorectal adenocarcinomas. Our conjugate offers a significant 100‐fold increase in performance compared to the RAPTA compound alone.

中文翻译：

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RAPTA 修饰的聚丙烯酰胺纳米粒子：探索它们的合成、物理特性和对细胞活力的影响

纳米药物：我们提出了一种新型纳米药物，由固定在聚丙烯酰胺纳米颗粒表面的 RAPTA 金属基药物组成。我们的偶联物已得到充分表征，并通过体外MTT 细胞毒性试验对 HT-29 结直肠腺癌评估了它们对细胞活力的影响。与单独的 RAPTA 化合物相比，我们的偶联物的性能显着提高了 100 倍。