Understanding the mechanisms underlying plants’ adaptation to their environment will require knowledge of the genes and alleles underlying elemental composition. Modern genetics is capable of quickly, and cheaply indicating which regions of DNA are associated with particular phenotypes in question, but most genes remain poorly annotated, hindering the identification of candidate genes. To help identify candidate genes underlying elemental accumulations, we have created the known ionome gene (KIG) list: a curated collection of genes experimentally shown to change uptake, accumulation, and distribution of elements. We have also created an automated computational pipeline to generate lists of KIG orthologs in other plant species using the PhytoMine database. The current version of KIG consists of 176 known genes covering 5 species, 23 elements, and their 1588 orthologs in 10 species. Analysis of the known genes demonstrated that most were identified in the model plant Arabidopsis thaliana, and that transporter coding genes and genes altering the accumulation of iron and zinc are overrepresented in the current list.

中文翻译：

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精选的影响植物离子组的基因

了解植物适应环境的机制将需要了解构成元素的基因和等位基因。现代遗传学能够快速，廉价地表明DNA的哪些区域与特定的表型有关，但是大多数基因的注释仍然很差，从而阻碍了候选基因的鉴定。为了帮助识别潜在的元素积累的候选基因，我们创建了一个已知的离子组基因（KIG）列表：经过实验证明可改变元素吸收，积累和分布的基因的精选集合。我们还创建了一条自动计算管道，以使用PhytoMine数据库生成其他植物物种中KIG直系同源物的列表。当前版本的KIG由176个已知基因组成，涵盖5种，23个元素，和他们的1588个直系同源物共10种。对已知基因的分析表明，大多数是在模型植物中鉴定出的拟南芥，以及转运蛋白编码基因和改变铁和锌积累的基因在当前清单中被过多代表。