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Development of Acanthocheilonema viteae in Meriones shawi: Absence of microfilariae and production of active ES‐62
Parasite Immunology ( IF 2.2 ) Pub Date : 2020-10-22 , DOI: 10.1111/pim.12803
Felicity E Lumb 1 , James Doonan 1 , Marlene Corbet 2 , Miguel A Pineda 2 , Margaret M Harnett 2 , William Harnett 1
Affiliation  

ES‐62 is a well‐studied anti‐inflammatory molecule secreted by L4‐adult stage Acanthocheilonema viteae. We maintain the life cycle of A viteae using Meriones libycus as the definitive host. Here, we investigated whether the full life cycle could be maintained, and functional ES‐62 produced, in a related jird species—Meriones shawi.

中文翻译:

在 Meriones shawi 中开发 Acanthocheilonema viteae:微丝蚴的缺失和活性 ES-62 的产生

ES-62 是一种经过充分研究的抗炎分子,由 L4 成年期Acanthocheilonema viteae分泌。我们使用Meriones libycus作为最终宿主来维持A vitaee的生命周期。在这里,我们调查了是否可以在相关的 jird 物种 - Meriones shawi 中维持完整的生命周期并产生功能性 ES-62 。
更新日期:2020-10-22
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