The nanozyme concept appeals to numerous scientists with interest in cancer catalytic therapy based on an easy and economic preparation with highly catalytic and stable properties compared to a natural enzyme. The supramolecular nanozyme is an especially efficient and simple method, which has been successful in biomedical applications by changing the redox state and reactive oxygen species in a cancer environment. Representative examples of nanozymes and supramolecular nanozymes in cancer catalytic therapy with respect to construction and development are displayed in this review. Emphasis is also placed on the supramolecular nanozyme materials and the inherent structure of those containing nanoparticles, hydrogels, nanovesicles, and the catalytic mechanism and reaction. The supramolecular nanozyme, promising for its special properties of selectivity, high catalytic capability and stability, could reveal the mysterious properties of the enzyme itself, and the efficient inhibition of the signaling channel in cancer catalytic therapy.

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基于超分子纳米酶的癌症催化治疗

纳米酶概念吸引了众多对癌症催化疗法感兴趣的科学家，该疗法基于一种简单且经济的制备方法，与天然酶相比具有高度催化和稳定的特性。超分子纳米酶是一种特别有效和简单的方法，通过改变癌症环境中的氧化还原状态和活性氧物质，在生物医学应用中取得了成功。本综述展示了纳米酶和超分子纳米酶在癌症催化治疗中的构建和发展方面的代表性例子。重点还放在了超分子纳米酶材料和那些含有纳米颗粒、水凝胶、纳米囊泡的材料的内在结构，以及催化机制和反应上。超分子纳米酶，