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Screening of In Vitro Antibacterial Property of Hematite (α-Fe 2 O 3 ) Nanoparticles: A Green Approach
Iranian Journal of Science and Technology, Transactions A: Science ( IF 1.7 ) Pub Date : 2020-10-20 , DOI: 10.1007/s40995-020-00995-0
Prashanna Suvaitha Sundara Selvam , Sangeetha Govindan , Bhavani Perumal , Venkatachalam Kandan

This study explores the fabrication of hematite (α-Fe2O3) nanoparticles utilizing aqueous extracts of Plectranthus amboinicus, which act as reducing and stabilizing agents. The prepared hematite (α-Fe2O3) nanoparticles have been characterized by TGA, PXRD, FT-IR, Raman, DRS UV–visible, Photoluminescence, SEM, Particle size distribution, and zeta potential measurements (DLS), respectively. According to the XRD reports, hematite (α-Fe2O3) nanoparticles are rhombohedral with a crystallite size of 7.0 nm. As of the FT-IR spectrum, the peaks attained at 544 and 447 cm−1 are attributes of Fe–O stretching in α-Fe2O3. As a result of Raman analysis, the existence of vibration modes of hematite (α-Fe2O3) nanoparticles was confirmed. Through the DRS UV–visible reflectance, the bandgap energy of hematite (α-Fe2O3) nanoparticles was detected to be 2.0 eV. The photoluminescence spectrum shows band edge emission at 552 nm. The morphology of hematite (α-Fe2O3) nanoparticles was aggregated with dense irregular shape and highly porous. Particle size distribution and zeta potential value of hematite (α-Fe2O3) nanoparticles were reported at 40 nm and − 35 mV, respectively. These nanoparticles exhibit strong antibacterial activity at a concentration of 30 μg/mL and also exhibit substantial minimum inhibition concentration value for gram-positive and gram-negative bacteria. The proposed strategy is therefore rapid, simple, cost-effective, and environmentally friendly which can be employed for the fabrication of hematite (α-Fe2O3) nanoparticles and can be used as a potent antibacterial agent.



中文翻译:

赤铁矿(α-Fe2 O 3)纳米粒子体外抗菌性能的筛选:绿色方法

本研究探讨赤铁矿的制造(的α-Fe 2 ö 3)纳米粒子利用的水提取物的左手香,其充当还原和稳定剂。将制备的赤铁矿(α-的Fe 2 ö 3)的纳米颗粒的特点是TGA,PXRD,FT-IR,拉曼光谱,DRS紫外可见,光致发光,SEM,粒度分布,和zeta电位测量(DLS),分别。根据XRD报告,赤铁矿(α-的Fe 2 ö 3)纳米颗粒是菱面体的具有7.0纳米的微晶尺寸。作为FT-IR光谱测定,在544和447厘米获得的峰-1是在拉伸的α-Fe的铁-O属性2O 3。拉曼分析的结果,赤铁矿的振动模式存在(的α-Fe 2 ö 3)纳米颗粒得到了证实。通过DRS紫外-可见反射率,赤铁矿的带隙能量(的α-Fe 2 ö 3)检测的纳米颗粒为2.0电子伏特。光致发光光谱显示在552nm处的带边缘发射。赤铁矿(α-铁形态2 ö 3)纳米粒子与密实的不规则的形状和高度多孔的聚合。颗粒尺寸分布和赤铁矿的ζ电势值(的α-Fe 2 ö 3纳米颗粒分别报道在40 nm和-35 mV下。这些纳米颗粒在浓度为30μg/ mL时显示出强大的抗菌活性,并且还显示出对革兰氏阳性和革兰氏阴性细菌的最低抑菌浓度值。所提出的策略因此快速,简单,这可用于(的α-Fe的赤铁矿的制造成本高,且环保2 ö 3)纳米颗粒和可被用作一种有效的抗菌剂。

更新日期:2020-10-20
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