Objective Folate deficiency is closely related to the occurrence of human tumors and plays an important role in cell growth, differentiation, repair, and host defense. We studied the effects of folic acid on the apoptosis of breast cancer cells (MDA-MB-231) and on the activity of the PTEN/AKT/P53 signaling pathway in breast cancer cells.

中文翻译：

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叶酸靶向的PTEN / AKT / P53信号通路促进乳腺癌细胞凋亡

目的叶酸缺乏与人类肿瘤的发生密切相关，在细胞生长，分化，修复和宿主防御中起着重要作用。我们研究了叶酸对乳腺癌细胞（MDA-MB-231）凋亡以及乳腺癌细胞PTEN / AKT / P53信号通路活性的影响。