Tourette syndrome (TS) is a neurodevelopmental condition characterized by multiple tics. Sensory symptoms play a key role in the clinical phenomenology and pathophysiology of TS, as most patients report premonitory urges driving tic expression. Interestingly, sensory symptoms have also been reported in other conditions characterized by repeated behaviors. This review explores the nature of sensory symptoms reported by patients with body focused repetitive behaviors (BFRBs, especially trichotillomania and skin picking disorder) and restless legs syndrome (RLS) in comparison to TS. A sense of mounting inner tension and reinforcement mechanisms driven by gratification and relief on expression of the tic or repetitive behavior appear to be implicated across all conditions. Subjective urges can be temporarily suppressed by patients with TS and selected BFRBs, whereas patients with RLS tend to report dysesthesia more frequently than a suppressible urge to move. The observed similarities in the phenomenology of sensory symptoms across these conditions raise the possibility of a comparable underlying pathophysiology. Preliminary findings suggest an overlap of neural pathways encompassing the insula, basal ganglia (putamen), and posterior cingulate cortex.

Tourette综合征（TS）是一种以多种抽动为特征的神经发育疾病。感官症状在TS的临床现象学和病理生理学中起着关键作用，因为大多数患者报告先兆促使驾驶tic表达。有趣的是，在以重复行为为特征的其他情况下也有感觉症状的报道。这篇综述探讨了与TS相比，以身体为中心的重复性行为（BFRB，尤其是毛滴虫病和皮肤采摘障碍）和躁动的腿综合征（RLS）的患者报告的感觉症状的性质。满足感和对抽动或重复性行为表达的满足感驱动着一种内在的张力和增强机制，这种感觉似乎与所有情况有关。TS和选定的BFRB患者可以暂时抑制主观冲动，而RLS患者倾向于报告感觉异常，而不是可移动的冲动。在这些情况下，感觉症状的现象学上观察到的相似性提高了潜在病理生理学可比性的可能性。初步发现提示神经通路重叠，包括岛突，基底神经节（丘脑）和扣带回皮层。