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Tyrosine hydroxylase containing neurons in the thalamic reticular nucleus of male Equids
Journal of Chemical Neuroanatomy ( IF 2.8 ) Pub Date : 2020-12-01 , DOI: 10.1016/j.jchemneu.2020.101873
Alexis S. Chaumeton , Nadine Gravett , Adhil Bhagwandin , Paul R. Manger

Here we report the unusual presence of thalamic reticular neurons immunoreactive for tyrosine hydroxylase in equids. The diencephalons of one adult male of four equid species, domestic donkey (Equus africanus asinus), domestic horse (Equus caballus), Cape mountain zebra (Equus zebra zebra) and plains zebra (Equus quagga), were sectioned in a coronal plane with series of sections stained for Nissl substance, myelin, or immunostained for tyrosine hydroxylase, and the calcium-binding proteins parvalbumin, calbindin and calretinin. In all equid species studied the thalamic reticular nucleus was observed as a sheet of neurons surrounding the rostral, lateral and ventral portions of the nuclear mass of the dorsal thalamus. In addition, these thalamic reticular neurons were immunopositive for parvalbumin, but immunonegative for calbindin and calretinin. Moreover, the thalamic reticular neurons in the equids studied were also immunopositive for tyrosine hydroxylase. Throughout the grey matter of the dorsal thalamus a terminal network also immunoreactive for tyrosine hydroxylase was present. Thus, the equid thalamic reticular neurons appear to provide a direct and novel potentially catecholaminergic innervation of the thalamic relay neurons. This finding is discussed in relation to the function of the thalamic reticular nucleus and the possible effect of a potentially novel catecholaminergic pathway on the neural activity of the thalamocortical loop.

中文翻译:

雄性马科动物丘脑网状核中含有酪氨酸羟化酶的神经元

在这里,我们报告了马科动物中酪氨酸羟化酶免疫反应性丘脑网状神经元的异常存在。四种马科动物,家驴 (Equus Africaus asinus)、家马 (Equus caballus)、开普山斑马 (Equus zebra zebra) 和平原斑马 (Equus quagga) 的 1 只成年雄性的间脑在冠状平面上被切片尼氏物质、髓磷脂染色或酪氨酸羟化酶免疫染色以及钙结合蛋白小清蛋白、钙结合蛋白和钙视网膜蛋白的切片。在所研究的所有马科动物中,丘脑网状核被观察为围绕背侧丘脑核团的嘴侧、外侧和腹侧部分的一层神经元。此外,这些丘脑网状神经元对小清蛋白呈免疫阳性,但对钙结合蛋白和钙视网膜蛋白呈免疫阴性。此外,所研究的马科动物丘脑网状神经元也对酪氨酸羟化酶呈免疫阳性。在整个背侧丘脑的灰质中,存在对酪氨酸羟化酶也具有免疫反应性的末端网络。因此,马丘脑网状神经元似乎提供了丘脑中继神经元的直接和新颖的潜在儿茶酚胺能神经支配。这一发现与丘脑网状核的功能和潜在的新型儿茶酚胺能通路对丘脑皮质环神经活动的可能影响进行了讨论。马丘脑网状神经元似乎为丘脑中继神经元提供了一种直接和新颖的潜在儿茶酚胺能神经支配。这一发现与丘脑网状核的功能和潜在的新型儿茶酚胺能通路对丘脑皮质环神经活动的可能影响进行了讨论。马丘脑网状神经元似乎为丘脑中继神经元提供了一种直接和新颖的潜在儿茶酚胺能神经支配。这一发现与丘脑网状核的功能和潜在的新型儿茶酚胺能通路对丘脑皮质环神经活动的可能影响进行了讨论。
更新日期:2020-12-01
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