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Chemical- and species-specific toxicity of nonylphenol and octylphenol to microalgae Chlorella pyrenoidosa and Scenedesmus obliquus
Environmental Toxicology and Pharmacology ( IF 4.3 ) Pub Date : 2020-10-17 , DOI: 10.1016/j.etap.2020.103517
Wenfeng Yang , Xinxin Gao , Yixiao Wu , Liang Wan , Chongyang Lu , Jiayi Huang , Houjiang Chen , Yuezhi Yang , Huijun Ding , Weihao Zhang

As typical endocrine disrupters, nonylphenol (NP) and octylphenol (OP) are emerging pollutants that have attracted wide attention. This study investigated the toxicity effects of NP and OP on microalgae Chlorella pyrenoidosa and Scenedesmus obliquus, particularly on their growth inhibition, photosynthetic pigment, chlorophyll fluorescence, and superoxide dismutase and malondialdehyde levels. Results showed that the 96 h EC50 of NP and OP was 2.89 and 5.21 mg/L on C. pyrenoidosa, respectively, and 1.54 and 8.48 mg/L on S. obliquus, respectively. NP exerted a stronger inhibitory effect on cell growth, photosynthesis, and PSII activity, and it contributed more oxidative stress on C. pyrenoidosa than on S. obliquus. By contrast, OP exerted a stronger inhibitory effect on S. obliquus than on C. pyrenoidosa. Furthermore, the toxicity of OP to the tested microalgae was lower than that of NP. Principal component analysis (PCA) and Pearson’s correlation indicate that the accumulation of reactive oxygen species is the dominant mechanism of NP and OP cellular toxicity. The principal components of NP and OP affecting microalgae are distinct in the PCA plot, and different endocrine disrupters have varying chemical-specific influences on algal cells. This study confirmed that the toxicity of NP and OP to microalgae C. pyrenoidosa and S. obliquus is chemical- and species-specific. These findings should be considered when assessing the health risk of environmental pollution.



中文翻译:

壬基酚和辛基酚对微藻藻类小球藻斜生藻的化学和物种特异性毒性

作为典型的内分泌干扰物,壬基酚(NP)和辛基酚(OP)是新兴的污染物,引起了广泛关注。本研究调查了NP和OP对微藻类小球藻小球藻斜生的毒性作用,特别是对它们的生长抑制,光合色素,叶绿素荧光,超氧化物歧化酶和丙二醛水平的影响。结果显示,在比氏梭状芽孢杆菌上,NP和OP的96 h EC 50分别为2.89和5.21 mg / L,对斜纹葡萄球菌分别为1.54和8.48 mg / L。NP对细胞生长,光合作用和PSII活性具有更强的抑制作用,并且对吡喃假单胞菌的氧化压力更大而不是斜生链球菌。相比之下,OP对斜生链球菌的抑制作用要比拟南芥假单胞菌强。此外,OP对被测微藻的毒性低于NP。主成分分析(PCA)和Pearson相关性表明,活性氧的积累是NP和OP细胞毒性的主要机制。在PCA图中,影响微藻的NP和OP的主要成分是不同的,并且不同的内分泌干扰物对藻类细胞具有不同的化学特异性影响。这项研究证实了NP和OP对微藻C.pyrenoidosaS.obliquus的毒性是特定于化学和物种的。在评估环境污染的健康风险时应考虑这些发现。

更新日期:2020-11-09
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