Alcohol misuse is long established as a contributor to the pathophysiology of the lung. The intersection of multi-organ responses to alcohol-mediated tissue injury likely contributes to the modulation of lung in response to injury. Indeed, the negative impact of alcohol on susceptibility to infection and on lung barrier function is now well documented. Thus, the alcohol lung represents a very likely comorbidity for the negative consequences of both COVID-19 susceptibility and severity. In this review, we present the known alcohol misuse ramifications on the lung in the context of the current coronavirus pandemic.

中文翻译：

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酒精使用障碍：COVID-19 的既往病史？

长期以来，酒精滥用一直被认为是导致肺部病理生理学的一个因素。对酒精介导的组织损伤的多器官反应的交叉可能有助于调节肺对损伤的反应。事实上，酒精对感染易感性和肺屏障功能的负面影响现已得到充分证明。因此，酒精肺很可能是导致 COVID-19 易感性和严重程度负面后果的合并症。在这篇综述中，我们介绍了在当前冠状病毒大流行的背景下已知的酒精滥用对肺部的影响。