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High-Throughput Sequencing Application in the Diagnosis and Discovery of Plant-Infecting Viruses in Africa, A Decade Later
Plants ( IF 4.658 ) Pub Date : 2020-10-16 , DOI: 10.3390/plants9101376
Jacques Davy Ibaba , Augustine Gubba

High-throughput sequencing (HTS) application in the field of plant virology started in 2009 and has proven very successful for virus discovery and detection of viruses already known. Plant virology is still a developing science in most of Africa; the number of HTS-related studies published in the scientific literature has been increasing over the years as a result of successful collaborations. Studies using HTS to identify plant-infecting viruses have been conducted in 20 African countries, of which Kenya, South Africa and Tanzania share the most published papers. At least 29 host plants, including various agricultural economically important crops, ornamentals and medicinal plants, have been used in viromics analyses and have resulted in the detection of previously known viruses and novel ones from almost any host. Knowing that the effectiveness of any management program requires knowledge on the types, distribution, incidence, and genetic of the virus-causing disease, integrating HTS and efficient bioinformatics tools in plant virology research projects conducted in Africa is a matter of the utmost importance towards achieving and maintaining sustainable food security.

中文翻译:

高通量测序在非洲植物感染病毒的诊断和发现中的应用,十年后

高通量测序(HTS)在植物病毒学领域中的应用始于2009年,已被证明在发现和检测已知病毒方面非常成功。在非洲大部分地区,植物病毒学仍是一门发展中的科学。多年来,由于成功的合作,科学文献中发表的与HTS相关的研究数量一直在增加。在20个非洲国家中进行了使用HTS识别植物感染性病毒的研究,其中肯尼亚,南非和坦桑尼亚的论文最多。至少29种寄主植物,包括各种具有重要经济意义的农作物,观赏植物和药用植物,已用于病毒学分析,并导致从几乎所有寄主中检测出先前已知的病毒和新型病毒。
更新日期:2020-10-17
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