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Advanced rules of relays
Nature Chemical Biology ( IF 14.8 ) Pub Date : 2020-10-16 , DOI: 10.1038/s41589-020-0632-8
Sonja Lorenz , Katrin Rittinger

Transfer of ubiquitin onto target proteins requires controlled interplay between E2 conjugating enzymes and E3 ligases. The structure of a trapped E2~Ub/RCR E3 transfer intermediate provides novel insight into the diversity of mechanisms used to fine tune this relay.

中文翻译:

继电器高级规则

泛素转移到目标蛋白上需要E2偶联酶和E3连接酶之间的受控相互作用。被困的E2〜Ub / RCR E3转移中间体的结构为微调该继电器提供了多种机制的新颖见解。
更新日期:2020-10-17
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