Aspergillus niger S17‐5 produces two alkylitaconic acids, 9‐hydroxyhexylitaconic acid (9‐HHIA) and 10‐hydroxyhexylitaconic acid (10‐HHIA), which have cytotoxic and polymer building block properties. In this study, we characterized the production of 9‐HHIA and 10‐HHIA by addition of their expected precursor, caprylic acid, to a culture of A. niger S17‐5, and demonstrated batch fermentation of 9‐HHIA and 10‐HHIA in a jar fermenter with DO‐stat.

中文翻译：

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辛酸增强黑曲霉S17-5中羟己基衣康酸的产生

黑曲霉S17-5产生两种烷基衣康酸，9-羟基己基衣康酸（9-HHIA）和10-羟基己基衣康酸（10-HHIA），它们具有细胞毒性和聚合物结构特性。在这项研究中，我们通过将预期的前体辛酸添加到黑曲霉S17-5的培养物中来表征9-HHIA和10-HHIA的生产，并证明了9-HHIA和10-HHIA的分批发酵具有DO-stat的广口瓶发酵罐。