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Salivary gland tumours in Iceland 1986–2015: a nationwide epidemiological analysis over a 30‐year time period
APMIS ( IF 2.8 ) Pub Date : 2020-10-16 , DOI: 10.1111/apm.13090
Anna Lilja Aegisdottir 1 , Geir Tryggvason 1, 2 , Anna Margret Jonsdottir 3 , Jon Gunnlaugur Jonasson 1, 3
Affiliation  

Salivary gland tumours (SGT) are a vast and heterogenous group of neoplasms. There is a relative lack of comprehensive nationwide epidemiological studies on the subject. The aim of this nationwide analysis was to gain insight into epidemiological traits, such as site, incidence and histological subtypes of SGT in general. Patients diagnosed with a primary SGT between 1986 and 2015 were identified from The Icelandic Cancer Registry and registries from all pathology departments in Iceland. Information on age, sex, tumour location and histology was retrieved from pathology reports. A total of 687 patients were diagnosed with a SGT, 609 (89%) were benign and 78 (11%) malignant. 9% of parotid gland tumours, 22% of submandibular gland tumours and 26% of minor SGT were malignant. The most common malignant tumours were mucoepidermoid carcinoma, acinic cell carcinoma and adenoid cystic carcinoma. The incidence of benign SGT was 4.9 per 100 000 among men and 7.0 per 100 000 among women. The incidence of malignant tumours was 0.59 per 100 000 for men and 0.79 per 100 000 for women. The proportion of malignant SGT is lower than most often reported. Only 10% of parotid gland tumours, 20% of submandibular gland tumours and 25% of minor salivary gland tumours are malignant.

中文翻译:

1986-2015年冰岛的涎腺肿瘤:30年时间内的全​​国流行病学分析

唾液腺肿瘤(SGT)是一大类异质性肿瘤。相对缺乏关于该主题的全国性流行病学研究。这项全国性分析的目的是深入了解流行病学特征,例如总体而言SGT的部位,发病率和组织学亚型。冰岛癌症登记处和冰岛所有病理部门的登记处均确定了1986年至2015年之间诊断为原发性SGT的患者。从病理报告中检索到有关年龄,性别,肿瘤位置和组织学的信息。共有687名患者被诊断为SGT,其中609名(89%)为良性,78名(11%)为恶性。腮腺肿瘤为9%,颌下腺肿瘤为22%,次要SGT为26%。最常见的恶性肿瘤是粘液表皮样癌,腺样细胞癌和腺样囊性癌。男性中良性SGT的发生率为4.9 / 100 000,女性中为7.0 / 100 000。男性恶性肿瘤的发病率为0.59 / 100 000,女性为0.79 / 100 000。恶性SGT的比例低于大多数报道。腮腺肿瘤只有10%,颌下腺肿瘤为20%,唾液腺轻微肿瘤为25%。
更新日期:2020-10-16
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