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RNA sequencing‐based long non‐coding RNA analysis and immunoassay in ovarian endometriosis
American Journal of Reproductive Immunology ( IF 3.6 ) Pub Date : 2020-10-16 , DOI: 10.1111/aji.13359
Jianlei Bi 1, 2 , Dandan Wang 1 , Liangyi Cui 1 , Qing Yang 1
Affiliation  

The mechanism underlying endometriosis is currently unknown. However, studies have indicated that immunity plays an important role in endometriosis occurrence and development. Long non‐coding RNAs (lncRNAs) do not encode proteins but participate in a variety of biological processes via different mechanisms. This study investigated differences in immune cells and immune‐related lncRNAs via high‐throughput RNA sequencing (RNA‐seq) analysis of ectopic and eutopic endometria with endometriosis.

中文翻译:

基于 RNA 测序的长链非编码 RNA 分析和免疫测定在卵巢子宫内膜异位症中的应用

子宫内膜异位症的潜在机制目前尚不清楚。但研究表明,免疫在子宫内膜异位症的发生和发展中起着重要作用。长链非编码 RNA (lncRNAs) 不编码蛋白质,但通过不同的机制参与各种生物过程。本研究通过对子宫内膜异位症的异位和在位子宫内膜进行高通量 RNA 测序 (RNA-seq) 分析,研究了免疫细胞和免疫相关 lncRNA 的差异。
更新日期:2020-10-16
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