Objective. While the positive correlation between impedance and noise of microelectrodes is well known, their quantitative relationship is too rarely described. Knowledge of this relationship provides useful information for both microsystems engineers and electrophysiologists. Approach. We discuss the physical basis of noise in recordings with microelectrodes, and compare measurements of impedance spectra to noise of microelectrodes. Main results. Microelectrode recordings intrinsically include thermal noise, ##IMG## [http://ej.iop.org/images/1741-2552/17/5/052001/jneabb3b4ieqn1.gif] {$v_\textrm{t} = \left[ 4 k_\textrm{B} T \int \textrm{Re} (Z) df \right] ^{1/2}$} , with the real component of impedance integrated over the recording frequency band. Impedance spectroscopy allows the quantitative prediction of thermal noise. Optimization of microelectrode noise should also consider the contribution of amplifier noise. These measures enable...

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微电极的噪声和阻抗

客观的。虽然微电极的阻抗和噪声之间的正相关是众所周知的，但它们的定量关系却很少被描述。这种关系的知识为微系统工程师和电生理学家提供了有用的信息。方法。我们讨论了微电极记录中噪声的物理基础，并将阻抗谱的测量值与微电极的噪声进行了比较。主要结果。微电极记录本质上包括热噪声，##IMG## [http://ej.iop.org/images/1741-2552/17/5/052001/jneabb3b4ieqn1.gif] {$v_\textrm{t} = \left [ 4 k_\textrm{B} T \int \textrm{Re} (Z) df \right] ^{1/2}$} ，阻抗的实部在记录频带上积分。阻抗谱允许对热噪声进行定量预测。微电极噪声的优化还应考虑放大器噪声的贡献。这些措施使...