We reported a simple protocol for the synthesis of gem-difluoroalkenes via a reaction sequence of hydroboration and 1,2-elimination of α,β-unsaturated carbonyl substrates under mild conditions. Two steps of this method could be executed in one pot. The β-CF2H- and β-CFH2-α,β-unsaturated carbonyls can be obtained smoothly from the α,β-unsaturated gem-difluoroamide with NaH as the base and via a boration–1,2-elimination sequence.

中文翻译：

---

通过硼氢化和 1,2-消除 α,β-不饱和羰基的序列合成 gem-二氟烯烃

我们报告了一个简单的协议，用于在温和条件下通过硼氢化和 1,2-消除 α,β-不饱和羰基底物的反应序列合成 gem-二氟烯烃。这种方法的两个步骤可以在一个锅中执行。β-CF2H-和β-CFH2-α,β-不饱和羰基化合物可以从α,β-不饱和钆-二氟酰胺以NaH为碱并通过硼化-1,2-消除序列顺利获得。