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The interaction of 5‐HTT variation, recent stress, and resilience on current anxiety levels in adolescents and young adults from the general population
Depression and Anxiety ( IF 7.4 ) Pub Date : 2020-10-14 , DOI: 10.1002/da.23101
Theresa M Ollmann 1 , Catharina Voss 1 , John Venz 1, 2 , Esther Seidl 1 , Jana Hoyer 1 , Hanna Kische 1 , Lars Pieper 1, 2 , Miriam A Schiele 3 , Katharina Domschke 3, 4 , Katja Beesdo-Baum 1, 2
Affiliation  

Previous work on gene‐environment (GxE) interplay concerning anxiety has focused on the interaction of 5‐HTTLPR with childhood adversities or traumatic events whereas the impact of recent stressors is understudied, as is the integration of resilience. The current study aimed to investigate the interactive effect of 5‐HTTLPR and recent stress on anxiety in adolescents considering resilience as buffer of a GxE risk constellation.

中文翻译:

5-HTT 变异、近期压力和复原力对普通人群中青少年和年轻人当前焦虑水平的相互作用

先前关于焦虑的基因-环境 (GxE) 相互作用的研究主要集中在5-HTT LPR 与童年逆境或创伤事件的相互作用上,而近期压力源的影响以及复原力的整合都没有得到充分研究。目前的研究旨在调查5-HTT LPR 和近期压力对青少年焦虑的交互影响,将弹性视为 GxE 风险星座的缓冲。
更新日期:2020-10-14
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