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Genome‐wide association study identifies markers associated with carcass and meat quality traits in Italian Large White pigs
Animal Genetics ( IF 2.4 ) Pub Date : 2020-10-14 , DOI: 10.1111/age.13013
M. C. Fabbri 1, 2 , M. Zappaterra 1 , R. Davoli 1 , P. Zambonelli 1
Affiliation  

A GWAS was performed using the genotypes obtained by PorcineSNP60 v2 BeadChip and 11 phenotypic traits (carcass lean meat percentage; backfat thickness; Longissimus thoracis muscle thickness; lightness; backfat thickness measured with caliper at the midline; meat pH measured at about 1 h post mortem and 24 h post mortem; CIE L*, a* and b* color parameters; and water‐holding capacity). Three markers were associated with three of the phenotypic traits considered: M1GA0009592 (SSC7) with backfat thickness and lean meat content, DIAS0002910 (SSC6) and ALGA0109856 (SSC6) with water‐holding capacity. The marker M1GA0009592, associated with backfat thickness, lies in a QTL region near the gene JARID2, which is a transcription factor also involved in the regulation of adipose‐derived stem cell pluripotency. The results seem to indicate a possible role of these genomic regions in the regulation of pig carcass fatness (i.e. backfat at last rib) and water‐holding capacity.

中文翻译:

全基因组关联研究确定了与意大利大型白猪car体和肉品质性状相关的标记

使用PorcineSNP60 v2 BeadChip获得的基因型和11个表型性状(car体瘦肉百分比;背脂肪厚度;朗吉斯胸肌厚度;轻度;背脂肪厚度在中线用卡尺测量;在宰后约1小时测量肉pH)进行GWAS验尸后24小时; CIE L *,a *和b *颜色参数;以及保水能力)。三个标记与所考虑的三个表型性状相关:具有背脂厚度和瘦肉含量的M1GA0009592(SSC7),具有持水能力的DIAS0002910(SSC6)和ALGA0109856(SSC6)。与后脂肪厚度相关的标记M1GA0009592位于基因JARID2附近的QTL区域,这是一种转录因子,也参与脂肪干细胞多能性的调节。结果似乎表明这些基因组区域可能在调节猪fat体脂肪(即最后肋骨的后脂肪)和持水能力中发挥作用。
更新日期:2020-11-04
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