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Metal Ion Promiscuity and Structure of 2,3‐Dihydroxybenzoic Acid Decarboxylase of Aspergillus oryzae
ChemBioChem ( IF 3.2 ) Pub Date : 2020-10-14 , DOI: 10.1002/cbic.202000600
Gerhard Hofer 1 , Xiang Sheng 2 , Simone Braeuer 3 , Stefan E Payer 4 , Katharina Plasch 4 , Walter Goessler 3 , Kurt Faber 4 , Walter Keller 1 , Fahmi Himo 2 , Silvia M Glueck 4
Affiliation  

On your metal: Elucidation of the unique Mg2+‐dependency of 2,3‐dihydroxybenzoic acid decarboxylase from Aspergillus oryzae, a member of the amidohydroalse superfamily, facilitates a better structure‐activity prediction of the potential biocatalyst, which is capable of catalyzing the regioselective ortho‐(de)carboxylation of phenol derivatives.
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中文翻译:

米曲霉2,3-二羟基苯甲酸脱羧酶的金属离子混杂性及结构

在您的金属上:阐明来自米曲霉的 2,3-二羟基苯甲酸脱羧酶的独特 Mg 2+依赖性,米曲霉是酰胺水解酶超家族的成员,有助于更好地预测潜在生物催化剂的结构-活性,该催化剂能够催化苯酚衍生物的区域选择性-(脱)羧化。
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更新日期:2020-10-14
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