当前位置: X-MOL 学术Lab. Anim. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Feeding management before gastrointestinal studies in pigs
Laboratory Animals ( IF 2.4 ) Pub Date : 2020-10-12 , DOI: 10.1177/0023677220960509
Rachael Gregson 1 , Stephen Greenhalgh 1 , Benjamin Cox 2 , Sandy Cochrane 3 , R Eddie Clutton 1
Affiliation  

Pigs are used to model humans in gastrointestinal (GI) studies because of their comparable size, physiology and behaviour: both are monogastric omnivores. A porcine surgical model for testing novel, tethered ultrasound capsule endoscopes (USCE) requires a clean, motile small intestine. Recommendations for human GI tract preparation before the mechanically similar process of video capsule endoscopy describe using oral purgatives, while high-carbohydrate drinks are recommended before colorectal surgery. Reports of the GI preparation of pigs exist but lack technical details, that is, administration, efficacy and side effects. This report details feeding a high-energy liquid diet to 11 female pigs undergoing surgery and USCE which was readily accepted and easily administered, and which produced a clean, motile small intestine and caused no detectable physiological/behavioural abnormalities.



中文翻译:

猪胃肠道研究前的饲养管理

由于猪的体型、生理和行为相似,猪在胃肠 (GI) 研究中被用来模拟人类:两者都是单胃杂食动物。用于测试新型系留超声胶囊内窥镜 (USCE) 的猪手术模型需要干净、活动的小肠。在机械类似视频胶囊内窥镜检查过程之前对人体胃肠道准备的建议描述了使用口服泻药,而在结直肠手术前建议使用高碳水化合物饮料。有关于猪胃肠道制剂的报道,但缺乏技术细节,即给药、功效和副作用。这份报告详细介绍了给 11 头接受手术和 USCE 的雌性猪喂食高能量流质饮食的细节,这种饮食很容易被接受和管理,并且产生了干净、

更新日期:2020-10-13
down
wechat
bug