Ti (IV)‐modified vinyl phosphate magnetic nanoparticles (Fe₃O₄@SiO₂@KH570‐PO₄‐Ti (IV)) was prepared for simultaneous extraction of multiple arsenic species, followed by high performance liquid chromatography (HPLC)– inductively coupled plasma mass spectrometry (ICP‐MS) analysis. Inorganic arsenic (iAs), dimethyl arsenic acid (DMA), monomethyl arsenic acid (MMA), p‐amino phenyl arsenic acid (p‐ASA), 4‐hdroxyphenylarsenic acid (4‐OH), phenyl arsenic acid (PAA), and 3‐nitro‐4‐hydroxyphenylarsenic acid (ROX) were investigated as interest analytes. It was found that they were quantitatively adsorbed on Fe₃O₄@SiO₂@KH570‐PO₄‐Ti (IV) at pH 5, and desorbed completely with 0.1 mol/L sodium hydroxide solution. Enrichment factor of 100‐fold was obtained by consuming 100 mL sample solution. Under the optimal conditions, the method combining MSPE with HPLC‐ICP‐MS presented a linear range of 1–5000 ng/L for seven arsenic species. The limits of detection were 0.39, 0.60, 0.23, 1.85, 0.54, 0.48, and 0.84 ng/L for DMA, MMA, p‐ASA, iAs, 4‐OH, PAA, ROX, with the relative standard deviations (c = 10 ng/L, n = 7) of 3.6, 3.9, 5.5, 12.4, 6.1, 5.8, 5.0, respectively. The accuracy of the method was validated by analyzing BCR 627 Tuna fish. The application potential of the method was further evaluated by chicken muscle and liver samples. No target arsenic species were detected in these samples, and good recoveries (80.6–123%) were obtained for the spiked samples at low, medium, and high concentration levels.

中文翻译：

---

Ti (IV) 改性的乙烯基磷酸酯磁性纳米粒子，用于同时预浓缩鸡肉样品中的多种砷，然后进行 HPLC-ICP-MS 分析

制备 Ti (IV) 改性的乙烯基磷酸酯磁性纳米粒子 (Fe ₃ O ₄ @SiO ₂ @KH570-PO ₄ -Ti (IV)) 用于同时提取多种砷物种，然后进行高效液相色谱 (HPLC)– 感应耦合等离子体质谱 (ICP-MS) 分析。无机砷 (iAs)、二甲基砷酸 (DMA)、单甲基砷酸 (MMA)、对氨基苯基砷酸 ( p -ASA)、4-羟基苯基砷酸 (4-OH)、苯基砷酸 (PAA) 和研究了 3-硝基-4-羟基苯砷酸 (ROX) 作为目标分析物。发现它们被定量吸附在 Fe ₃ O ₄ @SiO _{2 上}@KH570-PO ₄ -Ti (IV) 在 pH 5 下，用 0.1 mol/L 氢氧化钠溶液完全解吸。通过消耗 100 mL 样品溶液获得 100 倍的富集因子。在最佳条件下，MSPE 与 HPLC-ICP-MS 相结合的方法对七种砷物质的线性范围为 1-5000 ng/L。DMA、MMA、p- ASA、iAs、4-OH、PAA、ROX的检测限分别为0.39、0.60、0.23、1.85、0.54、0.48和 0.84 ng/L，相对标准偏差 ( c = 10纳克/升，n= 7) 分别为 3.6、3.9、5.5、12.4、6.1、5.8、5.0。通过分析 BCR 627 金枪鱼验证了该方法的准确性。通过鸡肌肉和肝脏样品进一步评估了该方法的应用潜力。在这些样品中未检测到目标砷形态，并且在低、中和高浓度水平的加标样品中获得了良好的回收率 (80.6–123%)。