The emergence of SARS‐CoV‐2 has caused global public health and economic crisis. Human leukocyte antigen (HLA) is a critical component of the viral antigen presentation pathway and plays essential roles in conferring differential viral susceptibility and severity of diseases. However, the association between HLA gene polymorphisms and risk for COVID‐19 has not been fully elucidated. We hypothesized that HLA genotypes might impact on the differences in morbidity and mortality of COVID‐19 across countries.

中文翻译：

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HLA基因多态性与COVID-19死亡率之间的关联：计算机分析

SARS-CoV-2的出现引起了全球公共卫生和经济危机。人白细胞抗原（HLA）是病毒抗原呈递途径的关键组成部分，在赋予差异性病毒易感性和疾病严重性方面起着至关重要的作用。但是，尚未完全阐明HLA基因多态性与COVID-19风险之间的关联。我们假设HLA基因型可能会影响各国间COVID-19发病率和死亡率的差异。