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The research of aptamer biosensor technologies for detection of microorganism
Applied Microbiology and Biotechnology ( IF 5 ) Pub Date : 2020-10-13 , DOI: 10.1007/s00253-020-10940-1
Jiecan Yi , Wen Xiao , Guiyin Li , Pian Wu , Yayuan He , Cuimei Chen , Yafei He , Ping Ding , Tianhan Kai

Abstract

The activities and transmissions of microorganisms are closely related to human, and all kinds of diseases caused by pathogenic microorganisms have attracted attention in the world and brought many challenges to human health and public health. The traditional microbial detection technologies have characteristics of longer detection cycle and complicated processes, therefore, which can no longer meet the detection requirements in the field of public health. At present, it is the focus to develop and design a novel, rapid, and simple microbial detection method in the field of public health. Herein, this article summarized the development of aptamer biosensor technologies for detection of microorganism in the aspect of bacteria, viruses, and toxins in detail, including optical aptamer sensors such as fluorometry and colorimetry, electrochemical aptamer sensors, and other technologies combined with aptamer.

Key points

Aptamer biosensor is a good platform for microbial detection.

Aptamer biosensors include optical sensors and electrochemical sensors.

Aptamer sensors have been widely used in the detection of bacteria, viruses, and other microorganisms.



中文翻译:

用于检测微生物的适体生物传感器技术的研究

摘要

微生物的活动和传播与人类息息相关,由病原微生物引起的各种疾病引起了世界的关注,给人类健康和公共卫生带来了诸多挑战。传统的微生物检测技术具有检测周期长,过程复杂的特点,已不能满足公共卫生领域的检测要求。目前,在公共卫生领域开发和设计一种新颖,快速,简单的微生物检测方法是重点。本文从细菌,病毒和毒素等方面详细概述了用于检测微生物的适体生物传感器技术的发展,包括荧光适体传感器,例如荧光法和比色法,

关键点

Aptamer生物传感器是微生物检测的良好平台。

适体生物传感器包括光学传感器和电化学传感器。

适体传感器已广泛用于检测细菌,病毒和其他微生物。

更新日期:2020-10-13
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