The removal of transmembrane proteins from the plasma membrane via endocytosis has emerged as powerful strategy in the regulation of receptor signalling and molecule transport. In the last decade, IRON‐REGULATED TRANSPORTER1 (IRT1) has been established as one of the key plant model proteins for studying endomembrane trafficking. The use of IRT1 and additional other metal transporters has uncovered novel factors involved in plant endocytosis and facilitated a better understanding of the role of endocytosis in the fine balancing of plant metal homoeostasis. In this review, we outline the specifics of plant endocytosis compared to what is known in yeast and mammals, and based on several examples, we demonstrate how studying metal transport has contributed to extending our knowledge of endocytic trafficking by shedding light on novel regulatory mechanisms and factors.

中文翻译：

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植物内吞作用：植物金属转运蛋白调控运输中的特性和作用

通过内吞作用从质膜上去除跨膜蛋白已成为调节受体信号传导和分子转运的有力策略。在过去十年中，铁调节转运蛋白 1 (IRT1) 已被确立为研究内膜转运的关键植物模型蛋白之一。IRT1 和其他其他金属转运蛋白的使用发现了涉及植物内吞作用的新因素，并有助于更好地理解内吞作用在植物金属稳态的精细平衡中的作用。在这篇综述中，我们概述了与酵母和哺乳动物中已知的相比，植物内吞作用的细节，并基于几个例子，