当前位置: X-MOL 学术Adv. Synth. Catal. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Umpolung Strategy with 2‐Aminothiophenols: Access to 2‐Arylbenzothiazine Derivatives from Alkyl Aryl Ketones
Advanced Synthesis & Catalysis ( IF 5.4 ) Pub Date : 2020-10-09 , DOI: 10.1002/adsc.202000964
Thanh Binh Nguyen 1 , Pascal Retailleau 1
Affiliation  

Strong Brønsted acids were found to catalyze the oxidative condensation of 2‐aminothiophenols with aryl alkyl ketones in DMSO to provide a wide range of complex 2‐arylbenzothiazines. With acetophenones, dimeric 2‐arylbenzothiazines were formed. On the other hand, the reaction with propiophenones resulted in 2:1 adducts whereas 1:1 adducts were produced with isobutyrophenones, benzoylacetonitrile and ethyl benzoylacetate.

中文翻译:

2-氨基硫酚的Umpolung策略:从烷基芳基酮获得2-芳基苯并噻嗪衍生物

发现强布朗斯台德酸可催化2-氨基硫酚与DMSO中的芳基烷基酮的氧化缩合反应,从而提供各种复杂的2-芳基苯并噻嗪。与苯乙酮一起形成了二聚2-芳基苯并噻嗪。另一方面,与丙苯酮的反应产生2∶1的加合物,而异丁苯酮,苯甲酰基乙腈和苯甲酰基乙酸乙酯产生1∶1的加合物。
更新日期:2020-12-08
down
wechat
bug