In order to create new functions of foldamer‐type hosts, various kinds of recognition arrays are expected to be developed. Here, a pyridine‐acetylene‐aniline unit is presented as a new class of a saccharide recognition array. The conformational stabilities of this array were analyzed by DFT calculation, and suggested that a pyridine‐acetylene‐aniline oligomer tends to form a helical structure. An oligomer of this array was synthesized, and its association for octyl β‐D‐glucopyranoside was confirmed by ¹H NMR measurements. UV/Vis, circular dichroism, and fluorescence titration experiments revealed its high affinity for octyl glycosides in apolar solvents (K_a=10⁴ to 10⁵ M⁻¹). This oligomer was relatively stable under basic conditions, and therefore this array was expected to be applied to the derivatization of saccharides. A 4‐(dialkylamino)pyridine attached pyridine‐acetylene‐aniline oligomer proved to catalyze the acylation of the octyl glucoside.

中文翻译：

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吡啶-乙炔-苯胺低聚物：糖的识别和此识别阵列对作为酰化催化剂活性的影响。

为了创建折叠式主机的新功能，预计将开发各​​种识别阵列。在这里，吡啶-乙炔-苯胺单元被作为一种新型的糖类识别阵列。通过DFT计算分析了该阵列的构象稳定性，表明吡啶-乙炔-苯胺低聚物趋于形成螺旋结构。合成了该阵列的低聚物，并通过¹ H NMR测量证实了其与辛基β -D-吡喃葡萄糖苷的缔合。UV / Vis，圆二色性和荧光滴定实验表明，它对非极性溶剂中的辛基糖苷具有很高的亲和力（K _a = 10 ⁴至10 ⁵  M ^-1）。该低聚物在碱性条件下相对稳定，因此预期该阵列可用于糖的衍生化。一种由4-（二烷基氨基）吡啶连接的吡啶-乙炔-苯胺低聚物被证明催化辛基糖苷的酰化作用。