当前位置: X-MOL 学术Chem. Asian J. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Activatable Off‐on Near‐Infrared QCy7‐based Fluorogenic Probes for Bioimaging
Chemistry - An Asian Journal ( IF 4.1 ) Pub Date : 2020-10-09 , DOI: 10.1002/asia.202001057
Xueqian Chen 1 , Yongning Bian 1 , Mingrui Li 1 , Yong Zhang 1 , Xueyun Gao 1 , Dongdong Su 1
Affiliation  

The activatable off‐on near‐infrared QCy7‐based fluorogenic probes have emerged as powerful modalities for detecting and monitoring biological analytes and understanding their biological processes in cells and organisms. The use of biomarker‐activated QCy7‐based probes enables simple synthesis, minimum photo‐damage to biological samples, and minimum background interference from biological systems. In this minireview, we aim to provide a rigorous but concise overview of activatable QCy7‐based fluorogenic probes by reporting the significant progress made in recent years. The design strategies and the main applications of accurate detection and imaging of disease‐related biomarkers (including ROS/RSS, enzymes, metal ions, and other related species) were reasonably analyzed and discussed. The potential challenges and prospects of activatable QCy7‐based fluorogenic probes are also emphasized to further advance the development of new methods for biomarker detection and bioimaging.

中文翻译:

可激活的基于近红外QCy7的生物成像荧光探针

可激活的基于近红外QCy7的荧光探针已成为检测和监测生物分析物并了解其在细胞和生物体中生物学过程的强大方式。使用基于QCy7的生物标记物激活的探针可以进行​​简单的合成,对生物样品的光损伤最小,并且对生物系统的背景干扰最小。在本小型审查中,我们旨在通过报告近年来取得的重大进展来提供对可激活的基于QCy7的荧光探针的严格而简洁的概述。合理分析和讨论了疾病相关生物标记物(包括ROS / RSS,酶,金属离子和其他相关物种)的准确检测和成像的设计策略和主要应用。
更新日期:2020-12-01
down
wechat
bug