Medicinal plants have always been utilized for the prevention and treatment of the spread of different diseases all around the world. To name some traditional medicine that has been used over centuries, we can refer to phytochemicals such as naringin, icariin, genistein, and resveratrol gained from plants. Osteogenic differentiation and mineralization of stem cells can be the result of specific bioactive compounds from plants. One of the most appealing choices for therapy can be mesenchymal stem cells (MSCs) because it has a great capability of self‐renewal and differentiation into three descendants, namely, endoderm, mesoderm, and ectoderm. Stem cell gives us the glad tidings of great advances in tissue regeneration and transplantation field for treatment of diseases. Using plant bioactive phytochemicals also holds tremendous promises in treating diseases such as osteoporosis. The purpose of the present review article thus is to investigate what are the roles and consequences of phytochemicals on osteogenic differentiation of MSCs.

中文翻译：

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植物化学物质对间充质干细胞成骨分化的影响

药用植物一直被用于预防和治疗世界各地不同疾病的传播。为了命名一些已经使用了几个世纪的传统药物，我们可以指代植物化学物质，例如从植物中提取的柚皮苷、淫羊藿苷、染料木素和白藜芦醇。干细胞的成骨分化和矿化可能是植物中特定生物活性化合物的结果。最吸引人的治疗选择之一是间充质干细胞 (MSCs)，因为它具有很强的自我更新和分化为三个后代的能力，即内胚层、中胚层和外胚层。干细胞为我们带来了组织再生和移植领域治疗疾病的重大进展的喜讯。使用植物生物活性植物化学物质在治疗骨质疏松症等疾病方面也具有巨大的前景。因此，本综述文章的目的是研究植物化学物质对 MSCs 成骨分化的作用和后果。