Background

Unknowing immunity status make migrants vaccine catch-up difficult. The interest of using a rapid tetanus immunotest as the Tétanos Quick Stick® (TQS®) to assess immunity status against tetanus has been evaluated in emergency rooms and it is now commonly used. The study aim was to evaluate TQS® as a tool for migrants’ vaccine catch-up.

Methods

From December 2018 to February 2019, a prospective study was performed and included consecutively migrants who attented to the primary medicine outconsultation of a health care centre in Paris. Migrants above 18, without any records of tetanus immunization were included and a TQS® was performed during a medical consultation. Adapted vaccine catch-up was then proposed. Immunity against tetanus among migrants, factors associated with positive TQS® and costs savings were evaluated.

Results

TQS® test was positive for 32% of the 310 included patients. In the univariable analysis, factors associated to the presence of a positive TQS® test were a female gender (OR = 1.69 CI95% [1.02–2.80]) and an urban living in the country of origin (OR = 1.79 CI95% [1.07–3.02]). In the multivariable analysis, these factors were not significantly associated to a positive TQS®. Anamnesis was not correlated to the immunity status: only 26% of the migrants who reported vaccinations in childhood, adolescence and adulthood had a positive TQS® test. The use of TQS® test allowed savings of 6,522 US$ as compared to the immediate catch-up strategy for the 310 patients.

Conclusion

The TQS® test is an acceptable, simple, rapid and cost saving test that could find a place in the migrants’ vaccine catch-up.

中文翻译：

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TétanosQuickStick®在没有事先接种证明的成人移民疫苗追赶中的实用性

背景

不知道免疫状况会使移民难以赶上疫苗。在急诊室已经评估了使用快速破伤风免疫测试作为TétanosQuickStick®（TQS®）评估针对破伤风的免疫状态的兴趣，目前已广泛使用它。研究目的是评估TQS®作为移民疫苗追赶的工具。

方法

从2018年12月到2019年2月，进行了一项前瞻性研究，并连续纳入了参加巴黎卫生保健中心主要药物咨询工作的移民。包括18岁以上，没有破伤风免疫记录的移民，并在医疗咨询期间进行了TQS®。然后提出了适应性疫苗追赶。评估了移民中针对破伤风的免疫力，与TQS®阳性相关的因素以及节省的成本。

结果

TQS®测试在310名患者中有32％呈阳性。在单变量分析中，与TQS®阳性检测相关的因素是女性（OR = 1.69 CI95％[1.02-2.80]）和居住在原籍国的城市（OR = 1.79 CI95％[1.07– 3.02]）。在多变量分析中，这些因素与正TQS®没有显着相关。回忆与免疫状态无关：只有26％的儿童，青少年和成年后接种疫苗的TQS®检测呈阳性。与310例患者的立即追赶策略相比，使用TQS®测试可节省6,522美元。

结论

TQS®测试是一种可以接受，简单，快速且节省成本的测试，可以在移民的疫苗追赶中找到一席之地。