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COVID-19 vaccine and boosted immunity: Nothing ad interim to do?
Vaccine ( IF 5.5 ) Pub Date : 2020-10-09 , DOI: 10.1016/j.vaccine.2020.10.013
Luca Roncati , Maria Vadalà , Veronica Corazzari , Beniamino Palmieri

Today, Coronavirus Disease 2019 (COVID-19) is a global public health emergency and vaccination measures to counter its diffusion are deemed necessary. Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the etiological agent of the disease, unleashes a T-helper 2 immune response in those patients requiring intensive care. Here, we illustrate the immunological mechanism to train the immune system towards a more effective and less symptomatic T-helper 1 immune response, to be exploited against SARS-CoV-2.



中文翻译:

COVID-19疫苗和增强的免疫力:暂时没有什么可做的?

如今,冠状病毒病2019(COVID-19)已成为全球公共卫生紧急事件,人们认为有必要采取疫苗接种措施来应对其扩散。该病的病原体重症急性呼吸系统综合症冠状病毒2(SARS-CoV-2)在需要重症监护的患者中释放T辅助2免疫反应。在这里,我们说明了免疫机制,以针对更严重,症状更少的T-helper 1免疫应答训练免疫系统,以对抗SARS-CoV-2。

更新日期:2020-10-30
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