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Impact of sleep on female and male reproductive functions: a systematic review
Fertility and Sterility ( IF 6.7 ) Pub Date : 2020-10-01 , DOI: 10.1016/j.fertnstert.2020.08.1429
Gabriela Caetano 1 , Inès Bozinovic 2 , Charlotte Dupont 3 , Damien Léger 4 , Rachel Lévy 3 , Nathalie Sermondade 3
Affiliation  

OBJECTIVE To evaluate the association of sleep parameters on female and male reproductive functions. DESIGN Systematic review. SETTING Not applicable. PATIENT(S) Female and male individuals, either healthy or infertile. INTERVENTION(S) Relevant articles were identified according to the The Preferred Reporting Items for Systematic Reviews and Meta-analyses recommendations in the PubMed and EMBASE databases from January 1, 2000 to June 8, 2020. MAIN OUTCOME MEASURE(S) The association between sleep and ovary function, spermatic function, natural fertility, and in vitro fertilization (IVF) outcomes was assessed. RESULT(S) A total of 33 studies that looked at the association between sleep and either ovary function (n = 10), spermatic function (n = 12), natural fertility (n = 5), or IVF outcomes (n = 6) were included. Overall, female and male fertility, as well as IVF outcomes may be affected by short sleep duration, evening chronotype, or shift/night work schedules. However, the results were hardly comparable due to the heterogeneous study methodologies used. CONCLUSION(S) Sleep may be an original and innovative parameter to consider in the reproduction field. Further investigation is needed to elucidate how sleep and fertility are interrelated and how sleep might constitute a useful modifiable target in infertility management.

中文翻译:

睡眠对女性和男性生殖功能的影响:系统评价

目的评估睡眠参数与女性和男性生殖功能的关系。设计系统审查。设置 不适用。患者 女性和男性个体,健康或不育。干预 相关文章是根据 PubMed 和 EMBASE 数据库从 2000 年 1 月 1 日到 2020 年 6 月 8 日期间系统评价和 Meta 分析的首选报告项目推荐确定的。主要结果测量评估了卵巢功能、精子功能、自然生育能力和体外受精 (IVF) 结果。结果(S) 共有 33 项研究着眼于睡眠与卵巢功能(n = 10)、精子功能(n = 12)、自然生育能力(n = 5)或 IVF 结果(n = 6)之间的关系被包括在内。总体而言,女性和男性的生育能力,以及 IVF 结果可能会受到睡眠时间短、晚上表型或轮班/夜间工作时间表的影响。然而,由于使用了异质的研究方法,结果几乎没有可比性。结论 睡眠可能是生殖领域需要考虑的一个原创性和创新性参数。需要进一步研究以阐明睡眠和生育力如何相互关联,以及睡眠如何构成不孕症管理中有用的可修改目标。
更新日期:2020-10-01
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