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Potential Inhibitors for SARS-CoV-2 and Functional Food Components as Nutritional Supplement for COVID-19: A Review
Plant Foods for Human Nutrition ( IF 4 ) Pub Date : 2020-10-10 , DOI: 10.1007/s11130-020-00861-9
Pushpendra Singh , Manish Kumar Tripathi , Mohammad Yasir , Ruchi Khare , Manoj Kumar Tripathi , Rahul Shrivastava

The severe acute respiratory syndrome is a viral respiratory infection and commonly called as COVID-19, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). It widely transmitted through direct or indirect contact. Currently, no specific treatment against SARS-CoV-2 are available; only prevention and supportive strategy are the preventive measures. The present review emphasizes the latest research related to COVID-19 and SARS-CoV-2 virus as well as the current status of potential inhibitors identified. Recent interest in SARS-CoV-2 has focused on transmission, symptoms, structure, and its structural proteins that exhibit promising therapeutics targets for rapid identification of potential inhibitors. The quick identification of potential inhibitors and immune-boosting functional food ingredients are crucial to combat this pandemic disease. We also tried to give an overview of the functional food components as a nutritional supplement, which helps in boosting our immune system and could be useful in preventing the COVID-19 and/or to improve the outcome during therapy.

中文翻译:

SARS-CoV-2 和功能性食品成分作为 COVID-19 营养补充剂的潜在抑制剂:综述

严重急性呼吸系统综合症是一种病毒性呼吸道感染,通常称为 COVID-19,由严重急性呼吸系统综合症冠状病毒-2 (SARS-CoV-2) 引起。它通过直接或间接接触广泛传播。目前,没有针对 SARS-CoV-2 的特定治疗方法;只有预防和支持策略才是预防措施。本综述强调了与 COVID-19 和 SARS-CoV-2 病毒相关的最新研究以及已确定的潜在抑制剂的现状。最近对 SARS-CoV-2 的兴趣集中在传播、症状、结构及其结构蛋白上,这些蛋白表现出有希望的治疗靶点,可以快速识别潜在的抑制剂。快速识别潜在抑制剂和增强免疫功能的功能性食品成分对于对抗这种流行病至关重要。我们还尝试概述作为营养补充剂的功能性食物成分,这有助于增强我们的免疫系统,并有助于预防 COVID-19 和/或改善治疗过程中的结果。
更新日期:2020-10-10
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