Marine algae play key roles in several medical, pharmaceutical, agricultural, and aquacultural applications. Furthermore, biosynthesized nanomaterials are becoming an alternative to conventional antibiotics in cost-effective, biocompatible, and non-toxic treatments for bacterial infections. This study features biogenic synthesis of silver nanoparticles using an aqueous extract of the marine red algae Pyropia yezoensis. The formation of silver nanoparticles was initially confirmed by UV–Vis spectroscopy and FTIR spectra were used to identify functional groups. The average crystalline size of the silver nanoparticles was around 20–22 nm, as determined by XRD analysis. Particle size was confirmed by SEM and TEM analyses, which also showed spherical particles without agglomeration. The antibacterial properties of the nanoparticles were assessed against both Gram-positive and Gram-negative bacterial cultures with significant activity observed against Gram negative P. aeruginosa. Our Pyropia yezoensis silver nanoparticles (P.y AgNPs) reduced the growth of P. aeruginosa at concentrations of 200 and 400 µg/ml. Our results strongly imply that P.y AgNPs may be useful in treating bacterial infections.

海藻在多种医学、制药、农业和水产养殖应用中发挥着关键作用。此外，生物合成纳米材料正在成为传统抗生素的替代品，用于治疗细菌感染的成本效益高、生物相容性好且无毒。这项研究的特点是使用海洋红藻Pyropia yezoensis的水提取物生物合成银纳米颗粒。银纳米粒子的形成最初是通过紫外-可见光谱和 FTIR 光谱来确定官能团的。通过 XRD 分析确定，银纳米颗粒的平均结晶尺寸约为 20-22 nm。粒径通过 SEM 和 TEM 分析确认，也显示球形颗粒没有团聚。针对革兰氏阳性和革兰氏阴性细菌培养物评估纳米颗粒的抗菌特性，观察到对革兰氏阴性铜绿假单胞菌具有显着活性。我们的Pyropia yezoensis银纳米粒子 ( Py AgNPs)在 200 和 400 µg/ml 的浓度下减少了铜绿假单胞菌的生长。我们的结果强烈暗示Py AgNPs 可用于治疗细菌感染。