Mesenchymal stem cells (MSCs) are an attractive tool to treat graft-versus-host disease because of their unique immunoregulatory properties. Although human bone marrow-derived MSCs (BM-MSCs) were the most widely used MSCs in cell therapy until recently, MSCs derived from human umbilical cords (UC-MSCs) have gained popularity as cell therapy material for their ethical and noninvasive collection.

中文翻译：

---

源自脐带和骨髓的人间充质干细胞以不同的机制发挥免疫调节作用。

间充质干细胞（MSC）由于其独特的免疫调节特性，是治疗移植物抗宿主病的有吸引力的工具。尽管直到最近，人骨髓来源的MSC（BM-MSC）仍是细胞治疗中使用最广泛的MSC，但源自人脐带（UC-MSC）的MSC已作为其伦理和非侵入性收集的细胞治疗材料而受到欢迎。