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Screening-level assessment of cancer risk associated with ambient air exposure in Aamjiwnaang First Nation
International Journal of Environmental Health Research ( IF 3.2 ) Pub Date : 2020-10-07 , DOI: 10.1080/09603123.2020.1827226
Kristian Larsen 1, 2 , Paleah Black 1 , Alison L Palmer 1 , Amanda J Sheppard 3, 4 , Sehar Jamal 3 , Sara Plain 5 , Cheryl Peters 1, 6, 7
Affiliation  

ABSTRACT

The manuscript reports findings from a screening-level assessment of cancer risk from outdoor air in Aamjiwnaang First Nation. Ambient air pollution can contribute to cardiovascular/respiratory diseases, and certain types of cancer. Certain communities may be at higher risk to the negative health impacts due to their geographical proximity to pollution sources. Outdoor air concentrations were mapped and the Lifetime Excess Cancer Risks (LECR) associated with long-term exposure to known carcinogens were estimated. LECR results for both benzene and 1,3-butadiene were above one per million. The LECR for benzene was 6.4 per million when the Health Canada slope factor was applied and 12.0 when using the US EPA. For 1,3-butadiene the LECR estimate was 8.8 per million. This work provides a better understanding of environmental exposures and potential associated cancer risks for residents in the Aamjiwnaang community and highlights the need for further air monitoring and a more detailed risk assessment.



中文翻译:

Aamjiwnaang 原住民与环境空气暴露相关的癌症风险筛查水平评估

摘要

该手稿报告了对 Aamjiwnaang 原住民户外空气中的癌症风险进行筛查水平评估的结果。环境空气污染会导致心血管/呼吸系统疾病和某些类型的癌症。由于地理位置靠近污染源,某些社区可能面临更高的负面健康影响风险。绘制了室外空气浓度图,并估计了与长期暴露于已知致癌物相关的终生癌症超额风险 (LECR)。苯和 1,3-丁二烯的 LECR 结果均高于百万分之一。应用加拿大卫生部斜率因子时苯的 LECR 为 6.4/百万,使用美国 EPA 时为 12.0。对于 1,3-丁二烯,LECR 估计为 8.8/百万。

更新日期:2020-10-07
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