Recent studies have shown that Salmonella shedding status affects sows' microbiota during gestation and that these modifications are reflected in the faecal microbiota of their piglets at weaning. The aims of this study were: 1) to evaluate the persistence, up to the fattening period, of the previously measured link between the microbiota of piglets and their mothers' Salmonella shedding status; and 2) measure the impact of the measured microbiota variations on their Salmonella excretion at this stage. To achieve this, 76 piglets born from 19 sows for which the faecal microbiota was previously documented, were selected in a multisite production system. The faecal matter of these swine was sampled after four weeks, at the fattening stage. The Salmonella shedding status and faecal microbiota of these animals were described using bacteriological and 16S rRNA gene amplicon sequencing, respectively. The piglet digestive microbiota association with the Salmonella shedding status of their sows did not persist after weaning and did not affect the risk of Salmonella excretion during fattening, while the birth mother still affected the microbiota of the swine at fattening. This supports the interest in sows as a target for potentially transferrable microbiota modifications.

中文翻译：

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母猪会影响仔猪的粪便微生物群直至育肥，但不会影响其肠道沙门氏菌的脱落状态

最近的研究表明，沙门氏菌脱落状态会影响母猪妊娠期间的微生物群，这些变化反映在断奶仔猪的粪便微生物群中。本研究的目的是： 1) 评估先前测量的仔猪微生物群与其母亲沙门氏菌脱落状态之间的持续性，直至育肥期；2) 在这个阶段测量所测量的微生物群变化对其沙门氏菌排泄的影响。为了实现这一目标，在多地点生产系统中选择了 19 头母猪出生的 76 头仔猪，这些母猪的粪便微生物群先前已被记录。四个星期后，在育肥阶段对这些猪的粪便进行取样。分别使用细菌学和 16S rRNA 基因扩增子测序来描述这些动物的沙门氏菌脱落状态和粪便微生物群。仔猪消化道微生物群与其母猪的沙门氏菌脱落状态的关联在断奶后并未持续存在，也不影响育肥期间沙门氏菌排泄的风险，而生母仍会影响肥育猪的微生物群。这支持了将母猪作为潜在可转移微生物群改造目标的兴趣。而生母在育肥时仍会影响猪的微生物群。这支持了将母猪作为潜在可转移微生物群改造目标的兴趣。而生母在育肥时仍会影响猪的微生物群。这支持了将母猪作为潜在可转移微生物群改造目标的兴趣。