Food allergen threshold dose-distributions are used in food allergen risk assessment to determine the level of risk within a food allergic population to a defined exposure amount of allergenic food protein and to help inform allergen risk management decisions. There has been a long-standing interest in determining threshold dose-distributions for different food allergens from a research and a risk management perspective.1-3 More recently, allergen risk management programs utilizing population threshold dose-distributions to inform the decision making process have been endorsed by multiple international stakeholder groups and national agencies.4-7 The interest shown by all stakeholders regarding this area of research had placed an emphasis on gathering as many data points, from as many foods, as possible to better inform allergen risk assessments and risk management.

中文翻译：

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低剂量、开放的食物挑战数据补充双盲、安慰剂对照数据在食物过敏原阈值剂量分布生成中的适用性

食品过敏原阈值剂量分布用于食品过敏原风险评估，以确定食品过敏人群中对规定的过敏原食物蛋白暴露量的风险水平，并帮助告知过敏原风险管理决策。从研究和风险管理的角度来确定不同食物过敏原的阈值剂量分布一直很受关注。 1-3 最近，利用人群阈值剂量分布为决策过程提供信息的过敏原风险管理计划已经得到多个国际利益相关者团体和国家机构的认可。 4-7 所有利益相关者对该研究领域表现出的兴趣都强调从尽可能多的食物中收集尽可能多的数据点，