The use of antimicrobials in veterinary medicine is under great scrutiny with the emergence of antimicrobial resistance in the human population. Equine veterinarians rely on antimicrobials as an essential tool for the treatment of infections in horses, but there is much criticism of some use, particularly prophylaxis. While the appropriate use of antimicrobials can be justified in equine medicine, the misuse cannot. The definition of appropriate use is complex and involves the indication for therapy, antimicrobial selection, dosing regimen and timing and route of administration, duration of therapy and modification of therapy based on microbial susceptibility and clinical response. The aim of this article is to provide guidance on these factors to assist equine veterinarians in determining what constitutes appropriate antimicrobial use in horses.

中文翻译：

---

抗菌药物用于治疗马细菌感染的概述

随着人类对抗菌素耐药性的出现，抗菌素在兽医学中的使用受到严格审查。马兽医依赖抗微生物药物作为治疗马感染的重要工具，但对某些用途，尤其是预防用途，存在很多批评。虽然在马药中适当使用抗菌药物是合理的，但滥用不能。适当使用的定义很复杂，涉及治疗适应症、抗菌素选择、给药方案、给药时机和途径、治疗持续时间以及基于微生物敏感性和临床反应的治疗调整。本文的目的是就这些因素提供指导，以帮助马兽医确定什么构成了马的适当抗菌药物使用。