Metabolic sources switch from carbohydrates in utero, to fatty acids after birth and then a mix once adults. O‐GlcNAcylation (O‐GlcNAc) is a post‐translational modification considered as a nutrient sensor. The purpose of this work was to assess changes in protein O‐GlcNAc levels, regulatory enzymes and metabolites during the first periods of life and decipher the impact of O‐GlcNAcylation on cardiac proteins.

中文翻译：

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蛋白质 O-GlcNAcylation 水平在大鼠出生后发育过程中以组织和时间特异性方式独立于膳食摄入量进行调节

代谢来源从子宫内的碳水化合物转变为出生后的脂肪酸，然后是成人后的混合物。O- GlcNAcylation ( O- GlcNAc) 是一种被认为是营养传感器的翻译后修饰。这项工作的目的是评估生命最初阶段蛋白O- GlcNAc 水平、调节酶和代谢物的变化，并破译O- GlcNAcylation 对心脏蛋白的影响。