In article number 2000383, Jinxiang Han, Yajun Liu, and co‐workers review how heavy metals induce bone damages through anemia‐independent and ‐related routes. Anemia‐independent routes include bone cell dysregulation, bone formation inhibition and bone degradation enhancement, and Ca/P homeostasis disruption. Stress erythropoiesis, erythropoietin deficiency, and disordered iron homeostasis are involved in anemia‐related routes.

中文翻译：

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重金属的影响：通过贫血依赖性地和独立地对重金属对骨细胞和骨代谢的不利影响（Adv。Sci。19/2020）

在2000383号文章中，韩金祥，刘亚军及其同事回顾了重金属如何通过与贫血无关的相关途径诱导骨骼损伤。不依赖贫血的途径包括骨细胞失调，骨形成抑制和骨降解增强以及Ca / P稳态破坏。贫血相关途径涉及应激性红细胞生成，促红细胞生成素缺乏和铁稳态紊乱。