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Near-complete nucleotide sequence of a border disease virus genotype BDV-7 isolate from Italy
Archives of Virology ( IF 2.7 ) Pub Date : 2020-10-06 , DOI: 10.1007/s00705-020-04836-8
Moira Bazzucchi , Ilaria Pierini , Monica Giammarioli , Gian Mario De Mia

To gain further insight into the genomic features of border disease virus (BDV), we determined the nearly complete genome sequence of isolate TO/121/04 from an aborted ovine fetus. Its genome contains a single open reading frame (ORF), which comprises 11,681 nucleotides encoding a polyprotein of 3893 amino acids. Phylogenetic analysis of the near full-length genome sequence showed that the BDV isolate differed significantly from all ovine pestiviruses identified so far, thus re-affirming the presence in Italy of this novel genetic group, termed BDV-7.



中文翻译:

来自意大利的边界病病毒基因型BDV-7分离物的近乎完整的核苷酸序列

为了进一步了解边界疾病病毒(BDV)的基因组特征,我们确定了来自流产绵羊胎儿的分离物TO / 121/04的近乎完整的基因组序列。它的基因组包含一个开放阅读框(ORF),其中包含11681个核苷酸,编码3893个氨基酸的多蛋白。对近乎全长的基因组序列进行的系统进化分析表明,BDV分离株与迄今鉴定出的所有绵羊瘟病毒均存在显着差异,因此再次证实了这一称为BDV-7的新遗传群体在意大利的存在。

更新日期:2020-10-07
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