Abstract

Recent studies reveal that glycerol monolaurate (GML) is regarded as an effective feed supplement in the production of broilers; however, the underlying mechanism remains unknown. The current study aimed to investigate how GML affected production performance and meat quality in yellow-feathered broilers. A total of 528 chicks were randomly assigned into four groups for a 56-day feeding trial. The control group received a basal diet, and the treated groups fed basal diet containing 300 (GML300), 450 (GML450), and 600 (GML600) mg/kg GML. Results revealed that dietary GML notably increased the average daily feed intake (p < 0.05) and body weight in broilers during 28–56 days of age and improved the duodenum and jejunum morphology. Dietary GML increased the total cholesterol in broilers (p < 0.05), but the hepatic, abdominal, and muscular fat deposition, as well as muscle fatty acids, were not affected. The flavor amino acids and total amino acids in muscle of GML300 and GML 450 groups were notably (p < 0.05) increased. GML supplementation selectively increased the colonization of an unclassified genus of Lachnospiraceae family and Bifidobacteriaceae, which were significantly (p < 0.05) correlated with the increase of muscle amino acids. Meanwhile, dietary GML notably increased short chain fatty acids content and the microbial DNA abundance of carbohydrate, amino acids and lipid metabolism pathway in cecum. These findings demonstrated that dietary GML improved performance, intestinal morphology, and muscle amino acids in broilers mainly by manipulating community, function and metabolites of gut microbiota.

Key points

• GML improves performance, muscle composition, and feed efficiency in broilers.

• GML alters gut microbiota community, function, and microbial metabolites in broilers.

• Improvements of broilers by GML closely associated with gut microbiota alteration.

中文翻译：

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单月桂酸甘油酯通过控制肠道微生物群来改善黄羽肉鸡的生产性能，肠道发育和肌肉氨基酸

摘要

最近的研究表明，单月桂酸甘油酯（GML）被视为肉鸡生产中的有效饲料补充剂。但是，其潜在机制仍然未知。当前的研究旨在调查GML如何影响黄羽肉鸡的生产性能和肉质。总共528只小鸡被随机分为四组进行为期56天的饲养试验。对照组接受基础饮食，治疗组饲喂基础饮食包含300（GML300），450（GML450）和600（GML600）mg / kg GML。结果表明，日粮GML显着提高了 28-56天龄肉鸡的平均日采食量（p <0.05）和体重，并改善了十二指肠和空肠形态。饮食中的GML会增加肉鸡的总胆固醇（p <0.05），但肝，腹和肌肉脂肪沉积以及肌肉脂肪酸均未受影响。GML300和GML 450组肌肉中的风味氨基酸和总氨基酸显着 增加（p <0.05）。GML的补充有选择地增加了钩螺科和双歧杆菌科的一个未分类属的定殖，这些显着（p <0.05）与肌肉氨基酸的增加相关。同时，饮食中的GML显着增加了盲肠中短链脂肪酸的含量以及碳水化合物，氨基酸和脂质代谢途径的微生物DNA丰度。这些发现表明，饮食中的GML主要通过控制肠道菌群的群落，功能和代谢产物来改善肉鸡的生产性能，肠道形态和肌肉氨基酸。

关键点

•GML可改善肉鸡的生产性能，肌肉组成和饲料效率。

•GML改变了肉鸡的肠道菌群，功能和微生物代谢产物。

•GML对肉鸡的改善与肠道菌群的改变密切相关。