Purpose: Proton energy-resolved dose imaging (pERDI) is a recently proposed technique to generate water equivalent path length (WEPL) images using a single detector. Owing to its simplicity in instrumentation, analysis and the possibility of using the in-room x-ray flat panels as detectors, this technique offers a promising avenue towards a clinically usable imaging system for proton therapy using scanned beams. The purpose of this study is to estimate the achievable accuracy in WEPL and Relative Stopping Power (RSP) using the pERDI technique and to assess the minimum dose required to achieve such accuracy. The novelty of this study is the first demonstration of the feasibility of pERDI technique in the pencil beam scanning (PBS) mode. Methods: A solid water wedge was placed in front of a 2D detector (Lynx). A library of energy-resolved dose functions (ERDF) was generated from the dose deposited in the detector by 50 PBS layers of energy varying from 100 MeV to 22...

中文翻译：

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笔形束扫描模式下能量分辨剂量成像技术的可行性

目的：质子能量分辨剂量成像 (pERDI) 是最近提出的使用单个探测器生成水等效路径长度 (WEPL) 图像的技术。由于其仪器、分析的简单性以及使用室内 X 射线平板作为探测器的可能性，该技术为使用扫描束进行质子治疗的临床可用成像系统提供了一条有希望的途径。本研究的目的是估计使用 pERDI 技术在 WEPL 和相对停止能力 (RSP) 中可实现的准确度，并评估实现这种准确度所需的最小剂量。这项研究的新颖之处在于首次证明了 pERDI 技术在笔形光束扫描 (PBS) 模式下的可行性。方法：将固体水楔放置在 2D 检测器 (Lynx) 的前面。