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Effect of receiver shape and volume on the Alzheimer disease for molecular communication via diffusion
IET Nanobiotechnology ( IF 2.3 ) Pub Date : 2020-10-05 , DOI: 10.1049/iet-nbt.2019.0300
Ibrahim Isik 1 , H Birkan Yilmaz 2 , Ilker Demirkol 3 , Mehmet Emin Tagluk 1
Affiliation  

Nano-devices are featured to communicate via molecular interaction, the so-called molecular communication (MC). In MC systems, the information is carried by molecules where the amount of molecules constitutes the level of the signal. In this study, an MC-based system was analysed with different receiver topology and related parameters, such as size, shape, and orientation of receptors on the receiver. Also in the concept of nano-medicine, the effect of amyloid-beta ( ), which is believed as the main cause of Alzheimer disease, on the successful reception ratio of molecules with the proposed receiver models was investigated. It was demonstrated that the cubic receiver model is superior to sphere one in terms of the correct reception ratio of the molecular signal. A cubic model where its edge (not rotated around the centre) is placed across the transmitter demonstrated a better performance in reducing the effect of as compared to the sphere model while a cubic model where its corner (rotated around the centre) is placed across the transmitter demonstrated a worse performance than the spherical model. From this expression, it may be concluded that with the adjustment of topological system parameters the probability of successful reception ratio in MC may be possible.

中文翻译:

接收器形状和体积对阿尔茨海默病通过扩散进行分子通讯的影响

纳米器件的特点是通过分子相互作用进行通信,即所谓的分子通信 (MC)。在 MC 系统中,信息由分子携带,其中分子的数量构成信号的水平。在这项研究中,分析了一个基于 MC 的系统,该系统具有不同的接收器拓扑和相关参数,例如接收器上接收器的大小、形状和方向。同样在纳米医学的概念中,β-淀粉样蛋白的作用( ),这被认为是阿尔茨海默病的主要原因,研究了分子与所提出的接收器模型的成功接收率。证明了立方接收器模型在分子信号的正确接收率方面优于球体一。将其边缘(不围绕中心旋转)放置在发射器上的立方模型在减少影响方面表现出更好的性能与球形模型相比,其角(围绕中心旋转)放置在发射器上的立方模型表现出比球形模型更差的性能。从这个表达式可以得出结论,随着拓扑系统参数的调整,MC中成功接收比的概率是可能的。
更新日期:2020-10-06
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