当前位置: X-MOL 学术Brain Sci. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Tractography-Based Analysis of Morphological and Anatomical Characteristics of the Uncinate Fasciculus in Human Brains
Brain Sciences ( IF 3.3 ) Pub Date : 2020-10-06 , DOI: 10.3390/brainsci10100709
Sara Kierońska , Paweł Sokal , Marta Dura , Magdalena Jabłońska , Marcin Rudaś , Renata Jabłońska

(1) Background: The uncinate fasciculus (UF) is a white matter bundle connecting the prefrontal cortex and temporal lobe. The functional role of the uncinate fasciculus is still uncertain. The role of the UF is attributed to the emotional empathy network. The present study aimed to more accurately the describe anatomical variability of the UF by focusing on the volume of fibers and testing for correlations with sex and age. (2) Material and Methods: Magnetic resonance imaging of adult patients with diffusion tensor imaging (DTI) was performed on 34 patients. The total number of fibers, volume of UF, and number of tracts were processed using DSI studio software. The DSI studio allows for mapping of different nerve pathways and visualizing of the obtained results using spatial graphics. (3) Results: The total number of UF tracts was significantly higher in the right hemisphere compared to the left hemisphere (right M ± SD = 52 ± 24; left: 39 ± 25, p < 0.05). A hook-shaped UF was the most common variant (91.7%). The UF volumes were larger in men (1410 ± 150.7 mm3) as compared to women (1325 ± 133.2 mm3) (p < 0.05). The mean fractional anisotropy (FA) values of the UF were significantly larger on the left side 0.597, while the right UF had an average of 0.346 (p < 0.05). Patients older than 50 years old had a significantly higher value of mean diffusivity (MD) (p = 0.034). In 73.5% of patients, a greater number of fibers terminated in the inferior part of the inferior frontal gyrus. (4) Conclusions: The morphological characteristics of the UF, unlike the shape, are associated with sex and are characterized by hemispheric dominance. These findings confirm the results of the previous studies. Future research should examine the potential correlation among the UF volume, number of fibers, and total brain volume in both sexes and patient psychological state.

中文翻译:

基于运动学的人脑筋膜筋膜的形态和解剖学特征分析

(1)背景:束状束(UF)是连接前额叶皮层和颞叶的白质束。束状束的功能性作用仍不确定。UF的作用归因于情感移情网络。本研究旨在通过关注纤维的体积并测试与性别和年龄的相关性,来更准确地描述超滤的解剖学变异性。(2)材料与方法:对34例成人患者进行磁共振成像,并进行弥散张量成像(DTI)。使用DSI Studio软件处理了纤维的总数,超滤量和束数。DSI工作室允许使用空间图形绘制不同的神经通路并可视化获得的结果。(3)结果:p<0.05)。钩状超滤膜是最常见的变体(91.7%)。男性(1410±150.7 mm 3)的UF体积大于女性(1325±133.2 mm 3)的UF体积(p <0.05)。UF的平均分数各向异性(FA)值在左侧0.597显着更大,而右侧UF的平均值为0.346(p <0.05)。50岁以上的患者的平均弥散度(MD)值显着更高(p= 0.034)。在73.5%的患者中,更多的纤维终止于额下回的下部。(4)结论:超滤的形态特征与形状不同,与性别有关,并具有半球优势。这些发现证实了先前研究的结果。未来的研究应检查男女和患者心理状态中超滤量,纤维数量和总脑容量之间的潜在相关性。
更新日期:2020-10-06
down
wechat
bug