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Biomechanical role of osteoporosis in the vibration characteristics of human spine after lumbar interbody fusion
International Journal for Numerical Methods in Biomedical Engineering ( IF 2.1 ) Pub Date : 2020-10-05 , DOI: 10.1002/cnm.3402
Qing-Dong Wang 1 , Li-Xin Guo 1
Affiliation  

Lumbar vertebrae osteoporosis is the most common challenge for lumbar interbody fusion, and this challenge has been widely concerned by scholars for many years. However, under whole‐body vibration, osteoporosis how to affect the vibration characteristics of the fusion lumbar spine, complications, and fusion outcomes is urgent to know. The L1‐L5 finite element model of lumbar spine was modified to simulate the transforaminal lumbar interbody fusion model with the bilateral pedicle screw fixator at L4‐L5 level. A 5 Hz, 40 N sinusoidal vertical load supplemented with a 400 N preload was used to simulate the vertical vibration of human body. The results showed that under whole‐body vibration, osteoporosis of fused vertebrae may cause the adjacent segments more unstable and increase the risk of adjacent segment diseases, subsidence, cage failure, rod failure, and lumbar instability. Osteoporosis of the fused vertebrae may cause the vertebral cells an unstable, inhibited growth and lead to poorer fusion outcomes. The findings may assist us in understanding the effect of osteoporosis on the vibration characteristics of lumbar spine fusion and provide references to clinical treatments for lumbar interbody fusion and lumbar vertebrae osteoporosis.

中文翻译:

骨质疏松对腰椎椎间融合术后人体脊柱振动特性的生物力学作用

腰椎骨质疏松是腰椎椎间融合术最常见的挑战,多年来这一挑战一直被学者广泛关注。然而,在全身振动下,骨质疏松症如何影响融合腰椎的振动特性、并发症和融合结果是迫切需要了解的。修改腰椎L1-L5有限元模型,模拟L4-L5水平双侧椎弓根螺钉固定器经椎间孔腰椎椎间融合模型。使用 5 Hz、40 N 正弦垂直载荷辅以 400 N 预载荷来模拟人体的垂直振动。结果表明,在全身振动下,融合椎体骨质疏松可能导致相邻节段更不稳定,增加相邻节段疾病、下沉、融合器失效、杆失效和腰椎不稳定。融合椎骨的骨质疏松症可能会导致椎骨细胞不稳定、生长受抑制并导致融合结果较差。该研究结果有助于我们了解骨质疏松症对腰椎融合器振动特性的影响,为腰椎椎间融合器和腰椎骨质疏松症的临床治疗提供参考。
更新日期:2020-12-10
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