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From Acetate to Bio-Based Products: Underexploited Potential for Industrial Biotechnology
Trends in Biotechnology ( IF 17.3 ) Pub Date : 2020-10-06 , DOI: 10.1016/j.tibtech.2020.09.004
Dirk Kiefer 1 , Manuel Merkel 1 , Lars Lilge 1 , Marius Henkel 1 , Rudolf Hausmann 1
Affiliation  

Currently, most biotechnological products are based on microbial conversion of carbohydrate substrates that are predominantly generated from sugar- or starch-containing plants. However, direct competitive uses of these feedstocks in the food and feed industry represent a dilemma, so using alternative carbon sources has become increasingly important in industrial biotechnology. A promising alternative carbon source that may be generated in substantial amounts from lignocellulosic biomass and C1 gases is acetate. This review discusses the underexploited potential of acetate to become a next-generation platform substrate in future industrial biotechnology and summarizes alternative sources and routes for acetate production. Furthermore, biotechnological aspects of microbial acetate utilization and the state of the art of biotechnological acetate conversion into value-added bioproducts are highlighted.



中文翻译:

从醋酸盐到生物基产品:工业生物技术的潜力未充分开发

目前,大多数生物技术产品基于碳水化合物底物的微生物转化,碳水化合物底物主要来自含糖或淀粉的植物。然而,这些原料在食品和饲料工业中的直接竞争用途代表了一种进退两难的境地,因此使用替代碳源在工业生物技术中变得越来越重要。可以从木质纤维素生物质和 C1 气体中大量产生的一种有前景的替代碳源是醋酸盐。本综述讨论了醋酸盐在未来工业生物技术中成为下一代平台底物的潜力,并总结了醋酸盐生产的替代来源和路线。此外,

更新日期:2020-10-06
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